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Water Uptake by Evaporating pMDI Aerosol Prior to Inhalation Affects Both Regional and Total Deposition in the Respiratory System

As pulmonary drug deposition is a function of aerosol particle size distribution, it is critical that the dynamics of particle formation and maturation in pMDI sprays in the interim between generation and inhalation are fully understood. This paper presents an approach to measure the evaporative and...

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Detalles Bibliográficos
Autores principales: Legh-Land, Victoria, Haddrell, Allen E., Lewis, David, Murnane, Darragh, Reid, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309010/
https://www.ncbi.nlm.nih.gov/pubmed/34202458
http://dx.doi.org/10.3390/pharmaceutics13070941