Cargando…

Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability

P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse structures out of cells, resulting in poor intestinal permeation and limited bioavailability following oral administration. P-gp inhibitors, including small molecule drugs, natural constituents, and pharmaceu...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Thi-Thao-Linh, Duong, Van-An, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309061/
https://www.ncbi.nlm.nih.gov/pubmed/34371794
http://dx.doi.org/10.3390/pharmaceutics13071103