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Effect of Carbon Chain Length, Ionic Strength, and pH on the In Vitro Release Kinetics of Cationic Drugs from Fatty-Acid-Loaded Contact Lenses

This paper explores the use of fatty acids in silicone hydrogel contact lenses for extending the release duration of cationic drugs. Drug release kinetics was dependent on the carbon chain length of the fatty acid loaded in the lens, with 12-, 14- and 18-carbon chain length fatty acids increasing th...

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Detalles Bibliográficos
Autores principales: Torres-Luna, Cesar, Hu, Naiping, Domszy, Roman, Fan, Xin, Yang, Jeff, Briber, Robert M., Wang, Nam Sun, Yang, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309118/
https://www.ncbi.nlm.nih.gov/pubmed/34371751
http://dx.doi.org/10.3390/pharmaceutics13071060

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