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Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream
Named after the two-faced Roman god of doorways, Janus kinases (JAKs) represent a class of tyrosine kinases. The JAK signaling pathway is pivotal for the downstream signaling of inflammatory cytokines, including interleukins, interferons, and multiple growth factors. This article provides an overvie...
Autores principales: | Smith, Paul, Yao, Wenqing, Shepard, Stacey, Covington, Maryanne, Lee, Jim, Lofland, Jennifer, Naim, Ahmad, Sheth, Trupti, Parikh, Bhavnish, Yeleswaram, Swamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309120/ https://www.ncbi.nlm.nih.gov/pubmed/34371735 http://dx.doi.org/10.3390/pharmaceutics13071044 |
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