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Ternary Complexes of pDNA, Neuron-Binding Peptide, and PEGylated Polyethyleneimine for Brain Delivery with Nano-Bubbles and Ultrasound
In brain-targeted delivery, the transport of drugs or genes across the blood−brain barrier (BBB) is a major obstacle. Recent reports found that focused ultrasound (FUS) with microbubbles enables transient BBB opening and improvement of drug or gene delivery. We previously developed nano-sized bubble...
Autores principales: | Endo-Takahashi, Yoko, Kurokawa, Ryo, Sato, Kanako, Takizawa, Nao, Katagiri, Fumihiko, Hamano, Nobuhito, Suzuki, Ryo, Maruyama, Kazuo, Nomizu, Motoyoshi, Takagi, Norio, Negishi, Yoichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309135/ https://www.ncbi.nlm.nih.gov/pubmed/34371694 http://dx.doi.org/10.3390/pharmaceutics13071003 |
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