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Oral Delivery of Nucleic Acids with Passive and Active Targeting to the Intestinal Tissue Using Polymer-Based Nanocarriers

Despite the apparent advantages for long-term treatment and local therapies against intestinal diseases, the oral delivery of nucleic acids has been challenging due to unfavorable physiological conditions for their stability. In this study, a novel nanodelivery system of PEG-PCL nanoparticles with e...

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Detalles Bibliográficos
Autores principales: Poudel, Sagun, Napit, Prabhat R., Briski, Karen P., Mattheolabakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309160/
https://www.ncbi.nlm.nih.gov/pubmed/34371766
http://dx.doi.org/10.3390/pharmaceutics13071075