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Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications

Chitosan has become a highlighted polymer, gaining paramount importance and research attention. The fact that this valuable polymer can be extracted from food industry-generated shell waste gives it immense value. Chitosan, owing to its biological and physicochemical properties, has become an attrac...

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Autores principales: Sivanesan, Iyyakkannu, Gopal, Judy, Muthu, Manikandan, Shin, Juhyun, Mari, Selvaraj, Oh, Jaewook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309384/
https://www.ncbi.nlm.nih.gov/pubmed/34301013
http://dx.doi.org/10.3390/polym13142256
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author Sivanesan, Iyyakkannu
Gopal, Judy
Muthu, Manikandan
Shin, Juhyun
Mari, Selvaraj
Oh, Jaewook
author_facet Sivanesan, Iyyakkannu
Gopal, Judy
Muthu, Manikandan
Shin, Juhyun
Mari, Selvaraj
Oh, Jaewook
author_sort Sivanesan, Iyyakkannu
collection PubMed
description Chitosan has become a highlighted polymer, gaining paramount importance and research attention. The fact that this valuable polymer can be extracted from food industry-generated shell waste gives it immense value. Chitosan, owing to its biological and physicochemical properties, has become an attractive option for biomedical applications. This review briefly runs through the various methods involved in the preparation of chitosan and chitosan nanoforms. For the first time, we consolidate the available scattered reports on the various attempts towards greens synthesis of chitosan, chitosan nanomaterials, and chitosan nanocomposites. The drug delivery applications of chitosan and its nanoforms have been reviewed. This review points to the lack of systematic research in the area of green synthesis of chitosan. Researchers have been concentrating more on recovering chitosan from marine shell waste through chemical and synthetic processes that generate toxic wastes, rather than working on eco-friendly green processes—this is projected in this review. This review draws the attention of researchers to turn to novel and innovative green processes. More so, there are scarce reports on the application of green synthesized chitosan nanoforms and nanocomposites towards drug delivery applications. This is another area that deserves research focus. These have been speculated and highlighted as future perspectives in this review.
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spelling pubmed-83093842021-07-25 Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications Sivanesan, Iyyakkannu Gopal, Judy Muthu, Manikandan Shin, Juhyun Mari, Selvaraj Oh, Jaewook Polymers (Basel) Review Chitosan has become a highlighted polymer, gaining paramount importance and research attention. The fact that this valuable polymer can be extracted from food industry-generated shell waste gives it immense value. Chitosan, owing to its biological and physicochemical properties, has become an attractive option for biomedical applications. This review briefly runs through the various methods involved in the preparation of chitosan and chitosan nanoforms. For the first time, we consolidate the available scattered reports on the various attempts towards greens synthesis of chitosan, chitosan nanomaterials, and chitosan nanocomposites. The drug delivery applications of chitosan and its nanoforms have been reviewed. This review points to the lack of systematic research in the area of green synthesis of chitosan. Researchers have been concentrating more on recovering chitosan from marine shell waste through chemical and synthetic processes that generate toxic wastes, rather than working on eco-friendly green processes—this is projected in this review. This review draws the attention of researchers to turn to novel and innovative green processes. More so, there are scarce reports on the application of green synthesized chitosan nanoforms and nanocomposites towards drug delivery applications. This is another area that deserves research focus. These have been speculated and highlighted as future perspectives in this review. MDPI 2021-07-09 /pmc/articles/PMC8309384/ /pubmed/34301013 http://dx.doi.org/10.3390/polym13142256 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sivanesan, Iyyakkannu
Gopal, Judy
Muthu, Manikandan
Shin, Juhyun
Mari, Selvaraj
Oh, Jaewook
Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications
title Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications
title_full Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications
title_fullStr Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications
title_full_unstemmed Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications
title_short Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications
title_sort green synthesized chitosan/chitosan nanoforms/nanocomposites for drug delivery applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309384/
https://www.ncbi.nlm.nih.gov/pubmed/34301013
http://dx.doi.org/10.3390/polym13142256
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