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Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain

Chronic pelvic pain (CPP) is a complex condition with a high economic and social burden. Although it is usually treated with botulinum neurotoxin type A (BoNT/A) injected into the pelvic floor muscles (PFM), its effect on their electrophysiological condition is unknown. In this study, 24 CPP patient...

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Autores principales: Albaladejo-Belmonte, Monica, Nohales-Alfonso, Francisco J., Tarazona-Motes, Marta, De-Arriba, Maria, Alberola-Rubio, Jose, Garcia-Casado, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309649/
https://www.ncbi.nlm.nih.gov/pubmed/34300408
http://dx.doi.org/10.3390/s21144668
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author Albaladejo-Belmonte, Monica
Nohales-Alfonso, Francisco J.
Tarazona-Motes, Marta
De-Arriba, Maria
Alberola-Rubio, Jose
Garcia-Casado, Javier
author_facet Albaladejo-Belmonte, Monica
Nohales-Alfonso, Francisco J.
Tarazona-Motes, Marta
De-Arriba, Maria
Alberola-Rubio, Jose
Garcia-Casado, Javier
author_sort Albaladejo-Belmonte, Monica
collection PubMed
description Chronic pelvic pain (CPP) is a complex condition with a high economic and social burden. Although it is usually treated with botulinum neurotoxin type A (BoNT/A) injected into the pelvic floor muscles (PFM), its effect on their electrophysiological condition is unknown. In this study, 24 CPP patients were treated with BoNT/A. Surface electromyographic signals (sEMG) were recorded at Weeks 0 (infiltration), 8, 12 and 24 from the infiltrated, non-infiltrated, upper and lower PFM. The sEMG of 24 healthy women was also recorded for comparison. Four parameters were computed: root mean square (RMS), median frequency (MDF), Dimitrov’s index (DI) and sample entropy (SampEn). An index of pelvic electrophysiological impairment (IPEI) was also defined with respect to the healthy condition. Before treatment, the CPP and healthy parameters of almost all PFM sides were significantly different. Post-treatment, there was a significant reduction in power (<RMS), a shift towards higher frequencies (>MDF), lower fatigue index (<DI) and increased information complexity (>SampEn) in all sites in patients, mainly during PFM contractions, which brought their electrophysiological condition closer to that of healthy women (<IPEI). sEMG can be used to assess the PFM electrophysiological condition of CPP patients and the effects of therapies such as BoNT/A infiltration.
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spelling pubmed-83096492021-07-25 Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain Albaladejo-Belmonte, Monica Nohales-Alfonso, Francisco J. Tarazona-Motes, Marta De-Arriba, Maria Alberola-Rubio, Jose Garcia-Casado, Javier Sensors (Basel) Article Chronic pelvic pain (CPP) is a complex condition with a high economic and social burden. Although it is usually treated with botulinum neurotoxin type A (BoNT/A) injected into the pelvic floor muscles (PFM), its effect on their electrophysiological condition is unknown. In this study, 24 CPP patients were treated with BoNT/A. Surface electromyographic signals (sEMG) were recorded at Weeks 0 (infiltration), 8, 12 and 24 from the infiltrated, non-infiltrated, upper and lower PFM. The sEMG of 24 healthy women was also recorded for comparison. Four parameters were computed: root mean square (RMS), median frequency (MDF), Dimitrov’s index (DI) and sample entropy (SampEn). An index of pelvic electrophysiological impairment (IPEI) was also defined with respect to the healthy condition. Before treatment, the CPP and healthy parameters of almost all PFM sides were significantly different. Post-treatment, there was a significant reduction in power (<RMS), a shift towards higher frequencies (>MDF), lower fatigue index (<DI) and increased information complexity (>SampEn) in all sites in patients, mainly during PFM contractions, which brought their electrophysiological condition closer to that of healthy women (<IPEI). sEMG can be used to assess the PFM electrophysiological condition of CPP patients and the effects of therapies such as BoNT/A infiltration. MDPI 2021-07-07 /pmc/articles/PMC8309649/ /pubmed/34300408 http://dx.doi.org/10.3390/s21144668 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Albaladejo-Belmonte, Monica
Nohales-Alfonso, Francisco J.
Tarazona-Motes, Marta
De-Arriba, Maria
Alberola-Rubio, Jose
Garcia-Casado, Javier
Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
title Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
title_full Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
title_fullStr Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
title_full_unstemmed Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
title_short Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
title_sort effect of bont/a in the surface electromyographic characteristics of the pelvic floor muscles for the treatment of chronic pelvic pain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309649/
https://www.ncbi.nlm.nih.gov/pubmed/34300408
http://dx.doi.org/10.3390/s21144668
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