lncRNA-PACER upregulates COX-2 and PGE2 through the NF-κB pathway to promote the proliferation and invasion of colorectal-cancer cells

BACKGROUND: p50-associated cyclooxygenase-2 extragenic RNA (PACER) is a recently identified antisense long non-coding RNA (lncRNA) located on the upstream of the promoter region of cyclooxygenase-2 (COX-2). Preliminary studies have suggested that PACER is involved in the regulation of COX-2 expressi...

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Detalles Bibliográficos
Autores principales: Sun, Peng, Quan, Ji-Chuan, Wang, Song, Zhuang, Meng, Liu, Zheng, Guan, Xu, Wang, Gui-Yu, Wang, Hong-Ying, Wang, Xi-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309685/
https://www.ncbi.nlm.nih.gov/pubmed/34316376
http://dx.doi.org/10.1093/gastro/goaa060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309685/
https://www.ncbi.nlm.nih.gov/pubmed/34316376
http://dx.doi.org/10.1093/gastro/goaa060

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