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Tracking HIV-1-Infected Cell Clones Using Integration Site-Specific qPCR

Efforts to cure HIV-1 infection require better quantification of the HIV-1 reservoir, particularly the clones of cells harboring replication-competent (intact) proviruses, termed repliclones. The digital droplet PCR assays commonly used to quantify intact proviruses do not differentiate among specif...

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Detalles Bibliográficos
Autores principales: Brandt, Leah D., Guo, Shuang, Joseph, Kevin W., Jacobs, Jana L., Naqvi, Asma, Coffin, John M., Kearney, Mary F., Halvas, Elias K., Wu, Xiaolin, Hughes, Stephen H., Mellors, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310066/
https://www.ncbi.nlm.nih.gov/pubmed/34202310
http://dx.doi.org/10.3390/v13071235