Cargando…

STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV)

Currently there is no FDA-licensed vaccine or therapeutic against Sudan ebolavirus (SUDV) infections. The largest ever reported 2014–2016 West Africa outbreak, as well as the 2021 outbreak in the Democratic Republic of Congo, highlight the critical need for countermeasures against filovirus infectio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Escaffre, Olivier, Juelich, Terry L., Neef, Natasha, Massey, Shane, Smith, Jeanon, Brasel, Trevor, Smith, Jennifer K., Kalveram, Birte, Zhang, Lihong, Perez, David, Ikegami, Tetsuro, Freiberg, Alexander N., Comer, Jason E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310124/ https://www.ncbi.nlm.nih.gov/pubmed/34372594 http://dx.doi.org/10.3390/v13071388

Ejemplares similares

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir
por: Comer, Jason E., et al.
Publicado: (2019)

Tilorone-Dihydrochloride Protects against Rift Valley Fever Virus Infection and Disease in the Mouse Model
por: Johnson, Kendra N., et al.
Publicado: (2021)

Favipiravir (T-705) protects against Nipah virus infection in the hamster model
por: Dawes, Brian E., et al.
Publicado: (2018)

Evaluations of rationally designed rift valley fever vaccine candidate RVax-1 in mosquito and rodent models
por: Ikegami, Tetsuro, et al.
Publicado: (2022)

The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection
por: Escaffre, Olivier, et al.
Publicado: (2023)

Rift Valley fever virus 78kDa envelope protein attenuates virus replication in macrophage-derived cell lines and viral virulence in mice
por: Terasaki, Kaori, et al.
Publicado: (2021)

Characterization of Ebola Virus Mucosal Challenge Routes in Cynomolgus Macaques
por: Johnson, Dylan M., et al.
Publicado: (2023)

Mucosal Challenge Ferret Models of Ebola Virus Disease
por: Brasel, Trevor, et al.
Publicado: (2021)

A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice
por: Terasaki, Kaori, et al.
Publicado: (2018)

Sudan Ebola virus (SUDV) outbreak in Uganda, 2022: lessons learnt and future priorities for sub-Saharan Africa
por: Bwire, Godfrey, et al.
Publicado: (2023)

Characterization of Rift Valley Fever Virus MP-12 Strain Encoding NSs of Punta Toro Virus or Sandfly Fever Sicilian Virus
por: Lihoradova, Olga A., et al.
Publicado: (2013)

Lessons Learned from Sudan Ebola Virus Disease (SUDV) Preparedness in Rwanda: A Comprehensive Review and Way Forward
por: Rwagasore, Edson, et al.
Publicado: (2023)

Evaluation of molnupiravir (EIDD-2801) efficacy against SARS-CoV-2 in the rhesus macaque model
por: Johnson, Dylan M., et al.
Publicado: (2023)

Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever
por: Gowen, Brian B., et al.
Publicado: (2013)

Functional Analysis of Rift Valley Fever Virus NSs Encoding a Partial Truncation
por: Head, Jennifer A., et al.
Publicado: (2012)

Polyphenylene carboxymethylene (PPCM) microbicide repurposed as antiviral against SARS-CoV-2. Proof of concept in primary human undifferentiated epithelial cells
por: Escaffre, Olivier, et al.
Publicado: (2021)

A Novel Bacterium-Like Particle-Based Vaccine Displaying the SUDV Glycoprotein Induces Potent Humoral and Cellular Immune Responses in Mice
por: Xu, Shengnan, et al.
Publicado: (2019)

Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model
por: Ikegami, Tetsuro, et al.
Publicado: (2017)

First vaccine approval under the FDA Animal Rule
por: Beasley, David W C, et al.
Publicado: (2016)

Hydrogen Sulfide Ameliorates SARS-CoV-2-Associated Lung Endothelial Barrier Disruption
por: Escaffre, Olivier, et al.
Publicado: (2023)

Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals
por: Escaffre, Olivier, et al.
Publicado: (2023)

Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease
por: Niemuth, Nancy A., et al.
Publicado: (2021)

Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses
por: Bazhanov, Nikolay, et al.
Publicado: (2017)

Differences in Genetic Diversity of Mammalian Tick-Borne Flaviviruses
por: Carpio, Kassandra L., et al.
Publicado: (2023)

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis
por: Johnson, Bryan A., et al.
Publicado: (2020)

Natural History of Marburg Virus Infection to Support Medical Countermeasure Development
por: Comer, Jason E., et al.
Publicado: (2022)

Chemotactic and Inflammatory Responses in the Liver and Brain Are Associated with Pathogenesis of Rift Valley Fever Virus Infection in the Mouse
por: Gray, Kimberly K., et al.
Publicado: (2012)

HIV prevalence and behavioral risk factors in the Sudan People’s Liberation Army: Data from South Sudan
por: Courtney, Lauren P., et al.
Publicado: (2017)

Multiplexed Digital mRNA Profiling of the Inflammatory Response in the West Nile Swiss Webster Mouse Model
por: Peña, José, et al.
Publicado: (2014)

To South Sudan with Operation Lifeline Sudan and UNICEF
por: Taylor-Robinson, Simon D
Publicado: (1999)

A STAT-1 knockout mouse model for Machupo virus pathogenesis
por: Bradfute, Steven B, et al.
Publicado: (2011)

Viral Resistance and IFN Signaling in STAT2 Knockout Fish Cells
por: Dehler, Carola E., et al.
Publicado: (2019)

A Synthetic Peptide CTL Vaccine Targeting Nucleocapsid Confers Protection from SARS-CoV-2 Challenge in Rhesus Macaques
por: Harris, Paul E., et al.
Publicado: (2021)

Anti-IL-6 Versus Anti-IL-6R Blocking Antibodies to Treat Acute Ebola Infection in BALB/c Mice: Potential Implications for Treating Cytokine Release Syndrome
por: Rubsamen, Reid, et al.
Publicado: (2020)

Port Sudan /
por: Rolin, Olivier
Publicado: (1995)

Comparative Burkholderia pseudomallei natural history virulence studies using an aerosol murine model of infection
por: Massey, Shane, et al.
Publicado: (2014)

Maternal and perinatal outcomes of dengue in PortSudan, Eastern Sudan
por: Adam, Ishag, et al.
Publicado: (2010)

Neonatal mortality in Sudan: analysis of the Sudan household survey, 2010
por: Bashir, Amal O, et al.
Publicado: (2013)

The Genetic Variation of Lactase Persistence Alleles in Sudan and South Sudan
por: Hollfelder, Nina, et al.
Publicado: (2021)

Targeted disruption of pi–pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity
por: Covés-Datson, Evelyn M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2oade2gfg7npuqv1h4n3sp9kej