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Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir

Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying drug resistance mutations can guide the clinical deployment of the antiviral and can addition...

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Detalles Bibliográficos
Autores principales: Soh, Y. Q. Shirleen, Malone, Keara D., Eguia, Rachel T., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310130/
https://www.ncbi.nlm.nih.gov/pubmed/34206520
http://dx.doi.org/10.3390/v13071196