Cargando…

Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform

Lujo virus (LUJV), a highly pathogenic arenavirus, was first identified in 2008 in Zambia. To aid the identification of effective therapeutics for LUJV, we developed a recombinant reporter virus system, confirming reporter LUJV comparability with wild-type virus and its utility in high-throughput an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Welch, Stephen R., Spengler, Jessica R., Genzer, Sarah C., Chatterjee, Payel, Flint, Mike, Bergeron, Éric, Montgomery, Joel M., Nichol, Stuart T., Albariño, César G., Spiropoulou, Christina F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310135/ https://www.ncbi.nlm.nih.gov/pubmed/34203149 http://dx.doi.org/10.3390/v13071255

Ejemplares similares

Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing
por: Shrivastava-Ranjan, Punya, et al.
Publicado: (2018)

Severe Hemorrhagic Fever in Strain 13/N Guinea Pigs Infected with Lujo Virus
por: Bird, Brian H., et al.
Publicado: (2012)

25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation
por: Shrivastava-Ranjan, Punya, et al.
Publicado: (2016)

Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin
por: Bergeron, Éric, et al.
Publicado: (2015)

A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus
por: Flint, Mike, et al.
Publicado: (2019)

Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases
por: Lo, Michael K., et al.
Publicado: (2020)

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture
por: Shrivastava-Ranjan, Punya, et al.
Publicado: (2020)

Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease
por: Welch, Stephen R., et al.
Publicado: (2022)

Development of a reverse genetics system for Sosuga virus allows rapid screening of antiviral compounds
por: Welch, Stephen R., et al.
Publicado: (2018)

Recombinant Marburg viruses containing mutations in the IID region of VP35 prevent inhibition of Host immune responses()
por: Albariño, César G., et al.
Publicado: (2014)

Recombinant Sudan virus and evaluation of humoral cross-reactivity between Ebola and Sudan virus glycoproteins after infection or rVSV-ΔG-ZEBOV-GP vaccination
por: Kainulainen, Markus H., et al.
Publicado: (2023)

Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever
por: Welch, Stephen R., et al.
Publicado: (2022)

Suboptimal Handling of Piccolo Samples or Reagent Discs for Consideration in Ebola Response
por: Spengler, Jessica R., et al.
Publicado: (2019)

Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles
por: Zivcec, Marko, et al.
Publicado: (2015)

The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model
por: Welch, Stephen R., et al.
Publicado: (2018)

Genetic Detection and Characterization of Lujo Virus, a New Hemorrhagic Fever–Associated Arenavirus from Southern Africa
por: Briese, Thomas, et al.
Publicado: (2009)

Lujo y capitalismo /
por: Sombart, Werner, 1863-1941
Publicado: (1965)

Lujo y capitalismo /
por: Sombart, Werner, 1863-1941
Publicado: (1979)

Lujo y capitalismo /
por: Sombart, Werner, 1863-1941
Publicado: (2009)

Genome Sequences of Crimean-Congo Hemorrhagic Fever Virus Strains Isolated in South Africa, Namibia, and Turkey
por: Zivcec, Marko, et al.
Publicado: (2017)

Small Interfering RNA Inhibition of Andes Virus Replication
por: Chiang, Cheng-Feng, et al.
Publicado: (2014)

The Crimean-Congo Hemorrhagic Fever Virus NSm Protein Is Dispensable for Growth In Vitro and Disease in Ifnar(-/-) Mice
por: Welch, Stephen R., et al.
Publicado: (2020)

Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination
por: Welch, Stephen R., et al.
Publicado: (2023)

Lujo, mentiras y marketing : ¿cómo funcionan las marcas de lujo? /
por: Sicard, Marie-Claude
Publicado: (2007)

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus
por: Zivcec, Marko, et al.
Publicado: (2016)

Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions
por: Scholte, F. E. M., et al.
Publicado: (2023)

El lujo del sol /
por: Campos, Julieta
Publicado: (1988)

De lujo y hambre
por: Garibay, Ricardo
Publicado: (1981)

El lujo del lenguaje
por: Tusón, Jesús
Publicado: (1989)

Una vida de lujo /
por: Lapidus, Jens, 1974-
Publicado: (2011)

Molecular Mechanisms Underlying the Cellular Entry and Host Range Restriction of Lujo Virus
por: Saito, Takeshi, et al.
Publicado: (2022)

Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice
por: Scholte, Florine E. M., et al.
Publicado: (2019)

Experimental infection of Egyptian rousette bats (Rousettus aegyptiacus) with Sosuga virus demonstrates potential transmission routes for a bat-borne human pathogenic paramyxovirus
por: Amman, Brian R., et al.
Publicado: (2020)

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection
por: Scholte, Florine E. M., et al.
Publicado: (2019)

Broad-spectrum in vitro antiviral activity of ODBG-P-RVn: an orally-available, lipid-modified monophosphate prodrug of remdesivir parent nucleoside (GS-441524)
por: Lo, Michael K., et al.
Publicado: (2021)

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar(-/-) mice
por: Welch, Stephen R., et al.
Publicado: (2019)

Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
por: Spengler, Jessica R., et al.
Publicado: (2015)

Hotel de lujo en Xalapa, Ver. :
por: García Carrillo, Rosa María
Publicado: (1977)

Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)
por: Lo, Michael K., et al.
Publicado: (2021)

Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells
por: Chiang, Cheng-Feng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3hdrrnc5vel3jgq80eofvcrptt