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Deletion of Kif5c Does Not Alter Prion Disease Tempo or Spread in Mouse Brain

In prion diseases, the spread of infectious prions (PrPSc) is thought to occur within nerves and across synapses of the central nervous system (CNS). However, the mechanisms by which PrPSc moves within axons and across nerve synapses remain undetermined. Molecular motors, including kinesins and dyne...

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Detalles Bibliográficos
Autores principales: Race, Brent, Williams, Katie, Baune, Chase, Striebel, James F., Winkler, Clayton W., Carroll, James A., Encalada, Sandra E., Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310152/
https://www.ncbi.nlm.nih.gov/pubmed/34372599
http://dx.doi.org/10.3390/v13071391