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CpG-ODN Signaling via Dendritic Cells-Expressing MyD88, but Not IL-10, Inhibits Allergic Sensitization

Allergen-specific T helper (Th)2 cells orchestrate upon allergen challenge the development of allergic eosinophilic lung inflammation. Sensitization with alum adjuvant, a type 2 adjuvant, has been used extensively in animal models of allergic lung disease. In contrast, type 1 adjuvants like CpG-ODN,...

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Detalles Bibliográficos
Autores principales: Alberca, Ricardo Wesley, Gomes, Eliane, Russo, Momtchilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310155/
https://www.ncbi.nlm.nih.gov/pubmed/34358159
http://dx.doi.org/10.3390/vaccines9070743