Genetic Analysis Reveals Differences in CD8(+) T Cell Epitope Regions That May Impact Cross-Reactivity of Vaccine-Induced T Cells against Wild-Type Mumps Viruses

Nowadays, mumps is re-emerging in highly vaccinated populations. Waning of vaccine-induced immunity plays a role, but antigenic differences between vaccine and mumps outbreak strains could also contribute to reduced vaccine effectiveness. CD8(+) T cells play a critical role in immunity to viruses. H...

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Detalles Bibliográficos
Autores principales: Kaaijk, Patricia, Emmelot, Maarten E., Kerkhof, Jeroen, van Els, Cécile A.C.M., Meiring, Hugo D., de Wit, Jelle, Bodewes, Rogier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310158/
https://www.ncbi.nlm.nih.gov/pubmed/34202193
http://dx.doi.org/10.3390/vaccines9070699

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