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In Vivo Production of HN Protein Increases the Protection Rates of a Minicircle DNA Vaccine against Genotype VII Newcastle Disease Virus

The Cre-recombinase mediated in vivo minicircle DNA vaccine platform (CRIM) provided a novel option to replace a traditional DNA vaccine. To further improve the immune response of our CRIM vaccine, we designed a dual promoter expression plasmid named pYL87 which could synthesize short HN protein und...

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Detalles Bibliográficos
Autores principales: Wang, Zhannan, Zhao, Xiaohan, Wang, Ying, Sun, Chao, Sun, Ming, Gao, Xingyun, Jia, Futing, Shan, Chenxin, Yang, Guilian, Wang, Jianzhong, Huang, Haibin, Shi, Chunwei, Yang, Wentao, Qian, Aidong, Wang, Chunfeng, Jiang, Yanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310180/
https://www.ncbi.nlm.nih.gov/pubmed/34358140
http://dx.doi.org/10.3390/vaccines9070723