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In Vivo Production of HN Protein Increases the Protection Rates of a Minicircle DNA Vaccine against Genotype VII Newcastle Disease Virus
The Cre-recombinase mediated in vivo minicircle DNA vaccine platform (CRIM) provided a novel option to replace a traditional DNA vaccine. To further improve the immune response of our CRIM vaccine, we designed a dual promoter expression plasmid named pYL87 which could synthesize short HN protein und...
Autores principales: | Wang, Zhannan, Zhao, Xiaohan, Wang, Ying, Sun, Chao, Sun, Ming, Gao, Xingyun, Jia, Futing, Shan, Chenxin, Yang, Guilian, Wang, Jianzhong, Huang, Haibin, Shi, Chunwei, Yang, Wentao, Qian, Aidong, Wang, Chunfeng, Jiang, Yanlong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310180/ https://www.ncbi.nlm.nih.gov/pubmed/34358140 http://dx.doi.org/10.3390/vaccines9070723 |
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