Development of a Quantitative One-Step RT-PCR Method for the Detection of Sabin 2 Virus Contamination in a Novel Oral Poliovirus Vaccine Type 2

To control circulating vaccine-derived type 2 poliovirus outbreaks, a more genetically stable novel Oral Poliovirus Vaccine type 2 (nOPV2) was developed by targeted modifications of Sabin 2 genome. Since the use of OPV2 made of Sabin 2 strain has been stopped, it is important to exclude the possibil...

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Detalles Bibliográficos
Autores principales: Manukyan, Hasmik, Tritama, Erman, Wahid, Rahnuma, Ansari, Azeem, Konz, John, Chumakov, Konstantin, Laassri, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310199/
https://www.ncbi.nlm.nih.gov/pubmed/34201447
http://dx.doi.org/10.3390/vaccines9070688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310199/
https://www.ncbi.nlm.nih.gov/pubmed/34201447
http://dx.doi.org/10.3390/vaccines9070688

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