Chk1 and the Host Cell DNA Damage Response as a Potential Antiviral Target in BK Polyomavirus Infection

The human BK polyomavirus (BKPyV) is latent in the kidneys of most adults, but can be reactivated in immunosuppressed states, such as following renal transplantation. If left unchecked, BK polyomavirus nephropathy (PyVAN) and possible graft loss may result from viral destruction of tubular epithelia...

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Detalles Bibliográficos
Autores principales: Hainley, Lydia E., Hughson, Martina S., Narendran, Amithi, Smith, Ralph, Arthur, Justin, Hayner-Buchan, Alida, Conti, David J., Lehman, John M., Friedrich, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310304/
https://www.ncbi.nlm.nih.gov/pubmed/34372559
http://dx.doi.org/10.3390/v13071353

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