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Relevance of 5-HT(2A) Receptor Modulation of Pyramidal Cell Excitability for Dementia-Related Psychosis: Implications for Pharmacotherapy

Psychosis occurs across a wide variety of dementias with differing etiologies, including Alzheimer’s dementia, Parkinson’s dementia, Lewy body dementia, frontotemporal dementia, and vascular dementia. Pimavanserin, a selective serotonin 5-HT(2A) receptor (5-HT(2A)R) inverse agonist, has shown promis...

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Detalles Bibliográficos
Autor principal: Burstein, Ethan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310514/
https://www.ncbi.nlm.nih.gov/pubmed/34224112
http://dx.doi.org/10.1007/s40263-021-00836-7

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