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A cell engineering approach to enzyme-based fed-batch fermentation

BACKGROUND: A fundamental problem associated with E. coli fermentations is the difficulty in achieving high cell densities in batch cultures, attributed in large part to the production and accumulation of acetate through a phenomenon known as overflow metabolism when supplying enough glucose for the...

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Detalles Bibliográficos
Autores principales: Sibley, Michael, Ward, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310608/
https://www.ncbi.nlm.nih.gov/pubmed/34303374
http://dx.doi.org/10.1186/s12934-021-01634-y