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A cell engineering approach to enzyme-based fed-batch fermentation
BACKGROUND: A fundamental problem associated with E. coli fermentations is the difficulty in achieving high cell densities in batch cultures, attributed in large part to the production and accumulation of acetate through a phenomenon known as overflow metabolism when supplying enough glucose for the...
Autores principales: | Sibley, Michael, Ward, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310608/ https://www.ncbi.nlm.nih.gov/pubmed/34303374 http://dx.doi.org/10.1186/s12934-021-01634-y |
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