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A metal-free salalen ligand with anti-tumor and synergistic activity in resistant leukemia and solid tumor cells via mitochondrial pathway

PURPOSE: Since the discovery of the well-known cis-platin, transition metal complexes are highly recognized as cytostatic agents. However, toxic side effects of the metal ions present in the complexes may pose significant problems for their future development. Therefore, we investigated the metal-fr...

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Detalles Bibliográficos
Autores principales: Hopff, Sina M., Wang, Qifang, Frias, Corazon, Ahrweiler, Marie, Wilke, Nicola, Wilke, Nathalie, Berkessel, Albrecht, Prokop, Aram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310854/
https://www.ncbi.nlm.nih.gov/pubmed/34213662
http://dx.doi.org/10.1007/s00432-021-03679-3