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The Good, the Bad, and the Deadly: Adenosinergic Mechanisms Underlying Sudden Unexpected Death in Epilepsy

Adenosine is an inhibitory modulator of neuronal excitability. Neuronal activity results in increased adenosine release, thereby constraining excessive excitation. The exceptionally high neuronal activity of a seizure results in a surge in extracellular adenosine to concentrations many-fold higher t...

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Detalles Bibliográficos
Autores principales: Purnell, Benton, Murugan, Madhuvika, Jani, Raja, Boison, Detlev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311182/
https://www.ncbi.nlm.nih.gov/pubmed/34321997
http://dx.doi.org/10.3389/fnins.2021.708304