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Obeticholic acid ameliorates obesity and hepatic steatosis by activating brown fat

Obeticholic acid (OCA) is exemplified as a potent drug for treating primary biliary cirrhosis and nonalcoholic fatty liver disease by inhibiting bile acid synthesis. However, it remains unclear whether the effect of OCA is mediated by the function of brown adipose tissue (BAT). In the present study,...

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Detalles Bibliográficos
Autores principales: Zhang, Hanlin, Dong, Meng, Liu, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311225/
https://www.ncbi.nlm.nih.gov/pubmed/34345273
http://dx.doi.org/10.3892/etm.2021.10423