Saxagliptin protects against diabetic nephropathy by inhibiting caspase 3/PARP-1-dependent nephrocyte apoptosis

Saxagliptin (SAX) can protect against tissue damage caused by diabetic nephropathy. However, whether this compound can restore kidney function, and its specific mechanism of action remain unclear. The present study explored the therapeutic effects and mechanisms of SAX. Male Wistar rats (8 weeks old...

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Detalles Bibliográficos
Autores principales: Xing, Xiaowei, Guo, Shuang, Liu, Yusheng, Kuang, Jiangying, Huang, Zhiwei, Wang, Xin, Lu, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311252/
https://www.ncbi.nlm.nih.gov/pubmed/34345272
http://dx.doi.org/10.3892/etm.2021.10422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311252/
https://www.ncbi.nlm.nih.gov/pubmed/34345272
http://dx.doi.org/10.3892/etm.2021.10422

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