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A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China

To elucidate current domestic factors influencing pharmacogenomics (PGx) implementation and its future in China, we conducted a questionnaire survey on PGx applications and testing. A questionnaire-based survey was created on the popular online professional survey platform “Wenjuanxing” (www.wjx.cn)...

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Autores principales: Guo, Chengxian, Hu, Biwen, Guo, Chengjun, Meng, Xiangguang, Kuang, Yun, Huang, Longjian, Wang, Danling, Xu, Kangwei, Zhao, Yanlin, Yang, Guoping, Cai, Weimin, Shu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311355/
https://www.ncbi.nlm.nih.gov/pubmed/34322018
http://dx.doi.org/10.3389/fphar.2021.682020
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author Guo, Chengxian
Hu, Biwen
Guo, Chengjun
Meng, Xiangguang
Kuang, Yun
Huang, Longjian
Wang, Danling
Xu, Kangwei
Zhao, Yanlin
Yang, Guoping
Cai, Weimin
Shu, Yan
author_facet Guo, Chengxian
Hu, Biwen
Guo, Chengjun
Meng, Xiangguang
Kuang, Yun
Huang, Longjian
Wang, Danling
Xu, Kangwei
Zhao, Yanlin
Yang, Guoping
Cai, Weimin
Shu, Yan
author_sort Guo, Chengxian
collection PubMed
description To elucidate current domestic factors influencing pharmacogenomics (PGx) implementation and its future in China, we conducted a questionnaire survey on PGx applications and testing. A questionnaire-based survey was created on the popular online professional survey platform “Wenjuanxing” (www.wjx.cn) and performed via the social media platform WeChat. Among 422 participants, there were physicians (27.7%), pharmacists (31.3%), and researchers (41.0%). We found that less than 50% of physicians were aware of the importance of PGx in drug therapy, while over 50% of pharmacists and researchers recognized the importance. Only 38.5% of physicians, 40.9% of pharmacists, and 55.5% of researchers concurred that PGx analysis could lower the economic burdens for patients. However, most of the responders affirmed that PGx should be effectively implemented in clinical practices. A lack of sector standards, a lack of clinical research, and a lack of guidelines were found to be the major factors for hindering PGx clinical application. Among drugs associated with PGx assays, the most common were warfarin and clopidogrel. Although PGx research has advanced rapidly in recent years in mainland China, the clinical implementation of PGx has a long way to go.
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spelling pubmed-83113552021-07-27 A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China Guo, Chengxian Hu, Biwen Guo, Chengjun Meng, Xiangguang Kuang, Yun Huang, Longjian Wang, Danling Xu, Kangwei Zhao, Yanlin Yang, Guoping Cai, Weimin Shu, Yan Front Pharmacol Pharmacology To elucidate current domestic factors influencing pharmacogenomics (PGx) implementation and its future in China, we conducted a questionnaire survey on PGx applications and testing. A questionnaire-based survey was created on the popular online professional survey platform “Wenjuanxing” (www.wjx.cn) and performed via the social media platform WeChat. Among 422 participants, there were physicians (27.7%), pharmacists (31.3%), and researchers (41.0%). We found that less than 50% of physicians were aware of the importance of PGx in drug therapy, while over 50% of pharmacists and researchers recognized the importance. Only 38.5% of physicians, 40.9% of pharmacists, and 55.5% of researchers concurred that PGx analysis could lower the economic burdens for patients. However, most of the responders affirmed that PGx should be effectively implemented in clinical practices. A lack of sector standards, a lack of clinical research, and a lack of guidelines were found to be the major factors for hindering PGx clinical application. Among drugs associated with PGx assays, the most common were warfarin and clopidogrel. Although PGx research has advanced rapidly in recent years in mainland China, the clinical implementation of PGx has a long way to go. Frontiers Media S.A. 2021-07-12 /pmc/articles/PMC8311355/ /pubmed/34322018 http://dx.doi.org/10.3389/fphar.2021.682020 Text en Copyright © 2021 Guo, Hu, Guo, Meng, Kuang, Huang, Wang, Xu, Zhao, Yang, Cai and Shu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Guo, Chengxian
Hu, Biwen
Guo, Chengjun
Meng, Xiangguang
Kuang, Yun
Huang, Longjian
Wang, Danling
Xu, Kangwei
Zhao, Yanlin
Yang, Guoping
Cai, Weimin
Shu, Yan
A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China
title A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China
title_full A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China
title_fullStr A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China
title_full_unstemmed A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China
title_short A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China
title_sort survey of pharmacogenomics testing among physicians, pharmacists, and researchers from china
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311355/
https://www.ncbi.nlm.nih.gov/pubmed/34322018
http://dx.doi.org/10.3389/fphar.2021.682020
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