Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring

A 48-year-old woman who had been receiving long-term interferon-β for 8 years for multiple sclerosis developed drug-induced World Health Organization group I pulmonary arterial hypertension. Triple therapy for pulmonary arterial hypertension and suspension of interferon-β led to improvement from a h...

Descripción completa

Detalles Bibliográficos
Autores principales: Raza, Farhan, Kozitza, Callyn, Chybowski, Amy, Goss, Kara N., Berei, Theodore, Runo, James, Eldridge, Marlowe, Chesler, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311374/
https://www.ncbi.nlm.nih.gov/pubmed/34317680
http://dx.doi.org/10.1016/j.jaccas.2021.02.005
_version_ 1783728948190904320
author Raza, Farhan
Kozitza, Callyn
Chybowski, Amy
Goss, Kara N.
Berei, Theodore
Runo, James
Eldridge, Marlowe
Chesler, Naomi
author_facet Raza, Farhan
Kozitza, Callyn
Chybowski, Amy
Goss, Kara N.
Berei, Theodore
Runo, James
Eldridge, Marlowe
Chesler, Naomi
author_sort Raza, Farhan
collection PubMed
description A 48-year-old woman who had been receiving long-term interferon-β for 8 years for multiple sclerosis developed drug-induced World Health Organization group I pulmonary arterial hypertension. Triple therapy for pulmonary arterial hypertension and suspension of interferon-β led to improvement from a high-risk to low-risk state and improvement in exercise hemodynamics, including vascular distensibility, and right ventricle–pulmonary artery coupling. (Level of Difficulty: Advanced.)
format Online
Article
Text
id pubmed-8311374
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-83113742021-07-26 Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring Raza, Farhan Kozitza, Callyn Chybowski, Amy Goss, Kara N. Berei, Theodore Runo, James Eldridge, Marlowe Chesler, Naomi JACC Case Rep Case Report A 48-year-old woman who had been receiving long-term interferon-β for 8 years for multiple sclerosis developed drug-induced World Health Organization group I pulmonary arterial hypertension. Triple therapy for pulmonary arterial hypertension and suspension of interferon-β led to improvement from a high-risk to low-risk state and improvement in exercise hemodynamics, including vascular distensibility, and right ventricle–pulmonary artery coupling. (Level of Difficulty: Advanced.) Elsevier 2021-04-14 /pmc/articles/PMC8311374/ /pubmed/34317680 http://dx.doi.org/10.1016/j.jaccas.2021.02.005 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Raza, Farhan
Kozitza, Callyn
Chybowski, Amy
Goss, Kara N.
Berei, Theodore
Runo, James
Eldridge, Marlowe
Chesler, Naomi
Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring
title Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring
title_full Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring
title_fullStr Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring
title_full_unstemmed Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring
title_short Interferon-β–Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring
title_sort interferon-β–induced pulmonary arterial hypertension: approach to diagnosis and clinical monitoring
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311374/
https://www.ncbi.nlm.nih.gov/pubmed/34317680
http://dx.doi.org/10.1016/j.jaccas.2021.02.005
work_keys_str_mv AT razafarhan interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT kozitzacallyn interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT chybowskiamy interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT gosskaran interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT bereitheodore interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT runojames interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT eldridgemarlowe interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring
AT cheslernaomi interferonbinducedpulmonaryarterialhypertensionapproachtodiagnosisandclinicalmonitoring

Ejemplares similares