The Composite of 3, 4-Dihydroxyl-Phenyl Lactic Acid and Notoginsenoside R1 Attenuates Myocardial Ischemia and Reperfusion Injury Through Regulating Mitochondrial Respiratory Chain

AIM: 3,4-Dihydroxyl-phenyl lactic acid (DLA) and notoginsenoside R1 (R1) are known to protect ischemia and reperfusion (I/R) injury by targeting Sirtuin1/NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10/the Mitochondrial Complex I (Sirt-1/NDUFA10/Complex I) and Rho-associated kinase/adenosine t...

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Detalles Bibliográficos
Autores principales: Yan, Li, Pan, Chun-Shui, Liu, Yu-Ying, Cui, Yuan-Chen, Hu, Bai-He, Chang, Xin, Wei, Xiao-Hong, Huang, Ping, Liu, Jian, Fan, Jing-Yu, Li, Quan, Sun, Kai, Yan, Lu-Lu, He, Ke, Han, Jing-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311465/
https://www.ncbi.nlm.nih.gov/pubmed/34322032
http://dx.doi.org/10.3389/fphys.2021.538962

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