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Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study

Osteoarthritis (OA) is a prevalent degenerative joint disease. Its development is highly associated with inflammatory response and apoptosis in chondrocytes. Selonsertib (Ser), the inhibitor of Apoptosis Signal-regulated kinase-1 (ASK1), has exhibited multiple therapeutic effects in several diseases...

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Detalles Bibliográficos
Autores principales:	Yan, Jiyuan, Zhang, Yingchi, Sheng, Gaohong, Ni, Bowei, Xiao, Yifan, Wang, Shanxi, Wang, Tianqi, Ma, Yongzhuang, Wang, Huaixi, Wu, Hua, Tu, Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311523/ https://www.ncbi.nlm.nih.gov/pubmed/34322020 http://dx.doi.org/10.3389/fphar.2021.687033

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