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To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End Protection

The regulation of DNA double-strand breaks (DSBs) and telomeres are diametrically opposed in the cell. DSBs are considered one of the most deleterious forms of DNA damage and must be quickly recognized and repaired. Telomeres, on the other hand, are specialized, stable DNA ends that must be protecte...

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Detalles Bibliográficos
Autores principales: Ackerson, Stephanie M., Romney, Carlan, Schuck, P. Logan, Stewart, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311741/
https://www.ncbi.nlm.nih.gov/pubmed/34322492
http://dx.doi.org/10.3389/fcell.2021.708763

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