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A Novel Method for Mendelian Randomization Analyses With Pleiotropy and Linkage Disequilibrium in Genetic Variants From Individual Data

Mendelian randomization makes use of genetic variants as instrumental variables to eliminate the influence induced by unknown confounders on causal estimation in epidemiology studies. However, with the soaring genetic variants identified in genome-wide association studies, the pleiotropy, and linkag...

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Detalles Bibliográficos
Autores principales:	Wang, Yuquan, Li, Tingting, Fu, Liwan, Yang, Siqian, Hu, Yue-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312241/ https://www.ncbi.nlm.nih.gov/pubmed/34322150 http://dx.doi.org/10.3389/fgene.2021.634394

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