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Sputum Gene Expression Reveals Dysregulation of Mast Cells and Basophils in Eosinophilic COPD

PURPOSE: The clinical and inflammatory associations of mast cells (MCs) and basophils in chronic obstructive pulmonary disease (COPD) are poorly understood. We previously developed and validated a qPCR-based MC/basophil gene signature in asthma to measure these cells in sputum samples. Here, we meas...

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Detalles Bibliográficos
Autores principales:	Winter, Natasha A, Gibson, Peter G, McDonald, Vanessa M, Fricker, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312253/ https://www.ncbi.nlm.nih.gov/pubmed/34321876 http://dx.doi.org/10.2147/COPD.S305380

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