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NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma
Osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), is effective in EGFR T790M positive non-small-cell lung cancer (NSCLC). Despite the efficacy of osimertinib, patients inevitably develop resistance and the mechanisms of osimertinib resistance ar...
Autores principales: | Li, Dan, Yang, DaFu, Cui, SaiQiong, Pan, Evenki, Yang, Peng, Dai, ZhaoXia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312323/ https://www.ncbi.nlm.nih.gov/pubmed/34321891 http://dx.doi.org/10.2147/OTT.S318250 |
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