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Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3

Background: Osteosarcoma (OS) is characterized by a high rate of metastasis. It has been found that tumor cells can bypass apoptosis which leads to an uncontrolled proliferation, but chloroquine (CQ) can have an effect on the tumors by inducing apoptosis. We aimed to explore the effects and the hypo...

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Detalles Bibliográficos
Autores principales: Chen, Chenglong, Zhang, Hongliang, Yu, Yiyang, Huang, Qingshan, Wang, Wei, Niu, Jianfang, Lou, Jingbing, Ren, Tingting, Huang, Yi, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312460/
https://www.ncbi.nlm.nih.gov/pubmed/34170850
http://dx.doi.org/10.18632/aging.203196