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Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3
Background: Osteosarcoma (OS) is characterized by a high rate of metastasis. It has been found that tumor cells can bypass apoptosis which leads to an uncontrolled proliferation, but chloroquine (CQ) can have an effect on the tumors by inducing apoptosis. We aimed to explore the effects and the hypo...
Autores principales: | Chen, Chenglong, Zhang, Hongliang, Yu, Yiyang, Huang, Qingshan, Wang, Wei, Niu, Jianfang, Lou, Jingbing, Ren, Tingting, Huang, Yi, Guo, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312460/ https://www.ncbi.nlm.nih.gov/pubmed/34170850 http://dx.doi.org/10.18632/aging.203196 |
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