Cargando…

Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review

Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuhlman, Justin J, Alhaj Moustafa, Muhamad, Gupta, Vivek, Jiang, Liuyan, Tun, Han W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312505/
https://www.ncbi.nlm.nih.gov/pubmed/34321945
http://dx.doi.org/10.2147/JBM.S325264
_version_ 1783729162453778432
author Kuhlman, Justin J
Alhaj Moustafa, Muhamad
Gupta, Vivek
Jiang, Liuyan
Tun, Han W
author_facet Kuhlman, Justin J
Alhaj Moustafa, Muhamad
Gupta, Vivek
Jiang, Liuyan
Tun, Han W
author_sort Kuhlman, Justin J
collection PubMed
description Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve plexuses and cranial nerves. The cauda equina is an anatomic structure located in the lower part of the spinal canal consisting of multiple lumbar and sacral nerve roots. Herein, we report a unique case of primary cauda equina diffuse large B-cell lymphoma presenting as a tumor mass in the lower spinal canal, which was treated with a CNS-centric treatment approach followed by autologous hematopoietic stem cell transplantation.
format Online
Article
Text
id pubmed-8312505
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-83125052021-07-27 Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review Kuhlman, Justin J Alhaj Moustafa, Muhamad Gupta, Vivek Jiang, Liuyan Tun, Han W J Blood Med Case Report Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve plexuses and cranial nerves. The cauda equina is an anatomic structure located in the lower part of the spinal canal consisting of multiple lumbar and sacral nerve roots. Herein, we report a unique case of primary cauda equina diffuse large B-cell lymphoma presenting as a tumor mass in the lower spinal canal, which was treated with a CNS-centric treatment approach followed by autologous hematopoietic stem cell transplantation. Dove 2021-07-21 /pmc/articles/PMC8312505/ /pubmed/34321945 http://dx.doi.org/10.2147/JBM.S325264 Text en © 2021 Kuhlman et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Kuhlman, Justin J
Alhaj Moustafa, Muhamad
Gupta, Vivek
Jiang, Liuyan
Tun, Han W
Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
title Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
title_full Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
title_fullStr Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
title_full_unstemmed Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
title_short Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
title_sort primary cauda equina lymphoma treated with cns-centric approach: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312505/
https://www.ncbi.nlm.nih.gov/pubmed/34321945
http://dx.doi.org/10.2147/JBM.S325264
work_keys_str_mv AT kuhlmanjustinj primarycaudaequinalymphomatreatedwithcnscentricapproachacasereportandliteraturereview
AT alhajmoustafamuhamad primarycaudaequinalymphomatreatedwithcnscentricapproachacasereportandliteraturereview
AT guptavivek primarycaudaequinalymphomatreatedwithcnscentricapproachacasereportandliteraturereview
AT jiangliuyan primarycaudaequinalymphomatreatedwithcnscentricapproachacasereportandliteraturereview
AT tunhanw primarycaudaequinalymphomatreatedwithcnscentricapproachacasereportandliteraturereview