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Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312505/ https://www.ncbi.nlm.nih.gov/pubmed/34321945 http://dx.doi.org/10.2147/JBM.S325264 |
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author | Kuhlman, Justin J Alhaj Moustafa, Muhamad Gupta, Vivek Jiang, Liuyan Tun, Han W |
author_facet | Kuhlman, Justin J Alhaj Moustafa, Muhamad Gupta, Vivek Jiang, Liuyan Tun, Han W |
author_sort | Kuhlman, Justin J |
collection | PubMed |
description | Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve plexuses and cranial nerves. The cauda equina is an anatomic structure located in the lower part of the spinal canal consisting of multiple lumbar and sacral nerve roots. Herein, we report a unique case of primary cauda equina diffuse large B-cell lymphoma presenting as a tumor mass in the lower spinal canal, which was treated with a CNS-centric treatment approach followed by autologous hematopoietic stem cell transplantation. |
format | Online Article Text |
id | pubmed-8312505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-83125052021-07-27 Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review Kuhlman, Justin J Alhaj Moustafa, Muhamad Gupta, Vivek Jiang, Liuyan Tun, Han W J Blood Med Case Report Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve plexuses and cranial nerves. The cauda equina is an anatomic structure located in the lower part of the spinal canal consisting of multiple lumbar and sacral nerve roots. Herein, we report a unique case of primary cauda equina diffuse large B-cell lymphoma presenting as a tumor mass in the lower spinal canal, which was treated with a CNS-centric treatment approach followed by autologous hematopoietic stem cell transplantation. Dove 2021-07-21 /pmc/articles/PMC8312505/ /pubmed/34321945 http://dx.doi.org/10.2147/JBM.S325264 Text en © 2021 Kuhlman et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Kuhlman, Justin J Alhaj Moustafa, Muhamad Gupta, Vivek Jiang, Liuyan Tun, Han W Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review |
title | Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review |
title_full | Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review |
title_fullStr | Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review |
title_full_unstemmed | Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review |
title_short | Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review |
title_sort | primary cauda equina lymphoma treated with cns-centric approach: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312505/ https://www.ncbi.nlm.nih.gov/pubmed/34321945 http://dx.doi.org/10.2147/JBM.S325264 |
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