A high-content platform for physiological profiling and unbiased classification of individual neurons

High-throughput physiological assays lose single-cell resolution, precluding subtype-specific analyses of activation mechanism and drug effects. We demonstrate APPOINT (automated physiological phenotyping of individual neuronal types), a physiological assay platform combining calcium imaging, roboti...

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Detalles Bibliográficos
Autores principales: DuBreuil, Daniel M., Chiang, Brenda M., Zhu, Kevin, Lai, Xiaofan, Flynn, Patrick, Sapir, Yechiam, Wainger, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312640/
https://www.ncbi.nlm.nih.gov/pubmed/34318289
http://dx.doi.org/10.1016/j.crmeth.2021.100004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312640/
https://www.ncbi.nlm.nih.gov/pubmed/34318289
http://dx.doi.org/10.1016/j.crmeth.2021.100004

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