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A Computational Study of Astrocytic GABA Release at the Glutamatergic Synapse: EAAT-2 and GAT-3 Coupled Dynamics
Neurotransmitter dynamics within neuronal synapses can be controlled by astrocytes and reflect key contributors to neuronal activity. In particular, Glutamate (Glu) released by activated neurons is predominantly removed from the synaptic space by perisynaptic astrocytic transporters EAAT-2 (GLT-1)....
Autores principales: | Flanagan, Bronac, McDaid, Liam, Wade, John Joseph, Toman, Marinus, Wong-Lin, KongFatt, Harkin, Jim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312685/ https://www.ncbi.nlm.nih.gov/pubmed/34322000 http://dx.doi.org/10.3389/fncel.2021.682460 |
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