Cargando…
A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients
COVID-19 disease outcome is highly dependent on adaptive immunity from T and B lymphocytes, which play a critical role in the control, clearance and long-term protection against SARS-CoV-2. To date, there is limited knowledge on the composition of the T and B cell immune receptor repertoires [T cell...
Autores principales: | Bieberich, Florian, Vazquez-Lombardi, Rodrigo, Yermanos, Alexander, Ehling, Roy A., Mason, Derek M., Wagner, Bastian, Kapetanovic, Edo, Di Roberto, Raphael Brisset, Weber, Cédric R., Savic, Miodrag, Rudolf, Fabian, Reddy, Sai T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312723/ https://www.ncbi.nlm.nih.gov/pubmed/34322127 http://dx.doi.org/10.3389/fimmu.2021.701085 |
Ejemplares similares
-
SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display
por: Ehling, Roy A., et al.
Publicado: (2022) -
Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes
por: Yermanos, Alexander, et al.
Publicado: (2021) -
Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells
por: Neumeier, Daniel, et al.
Publicado: (2022) -
Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires
por: Miho, Enkelejda, et al.
Publicado: (2018) -
immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking
por: Weber, Cédric R, et al.
Publicado: (2020)