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3: IGF-1 Hydrogel-based Nanofiber Drug Delivery System to Improve Nerve Regeneration and Functional Recovery After Peripheral Nerve Repair
PURPOSE: Insulin-like growth factor 1 (IGF-1) is a potent mitogen with the potential to enhance axonal regeneration and minimize muscle atrophy and Schwann cell senescence following prolonged denervation after peripheral nerve injury. IGF-1 is a small protein with a half-life of 5 min, making local...
Autores principales: | Harris, Thomas G.W., Qiu, Chenhu, Sarhane, Karim, von Guionneau, Nicholas, Glass, Connor, Segna, Kara, Wong, Alison, Hanwright, Philip, Malapati, Harsha, Hricz, Nicholas, Generoso, Matthew, Hōke, Ahmet, Mao, Hai-Quan, Tuffaha, Sami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312795/ http://dx.doi.org/10.1097/01.GOX.0000769996.07502.ab |
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