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A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study

BACKGROUND: Water, sanitation and hygiene (WASH) interventions should support infant growth but trial results are inconsistent. Frequently, interventions do not consider behaviours or transmission pathways specific to age. A household playspace (HPS) is one intervention component which may block fae...

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Autores principales: Budge, Sophie, Hutchings, Paul, Parker, Alison, Tyrrel, Sean, Norton, Sam, Garbutt, Camila, Woldemedhin, Fitsume, Jemal, Mohammed Yasin, Moges, Mathewos, Hussen, Siraj, Beyene, Hunachew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312948/
https://www.ncbi.nlm.nih.gov/pubmed/34260591
http://dx.doi.org/10.1371/journal.pntd.0009514
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author Budge, Sophie
Hutchings, Paul
Parker, Alison
Tyrrel, Sean
Norton, Sam
Garbutt, Camila
Woldemedhin, Fitsume
Jemal, Mohammed Yasin
Moges, Mathewos
Hussen, Siraj
Beyene, Hunachew
author_facet Budge, Sophie
Hutchings, Paul
Parker, Alison
Tyrrel, Sean
Norton, Sam
Garbutt, Camila
Woldemedhin, Fitsume
Jemal, Mohammed Yasin
Moges, Mathewos
Hussen, Siraj
Beyene, Hunachew
author_sort Budge, Sophie
collection PubMed
description BACKGROUND: Water, sanitation and hygiene (WASH) interventions should support infant growth but trial results are inconsistent. Frequently, interventions do not consider behaviours or transmission pathways specific to age. A household playspace (HPS) is one intervention component which may block faecal-oral transmission. This study was a two-armed, parallel-group, randomised, controlled feasibility trial of a HPS in rural Ethiopia. It aimed to recommend proceeding to a definitive trial. Secondary outcomes included effects on infant health, injury prevention and women’s time. METHODS: November 2019−January 2020 106 households were identified and assessed for eligibility. Recruited households (N = 100) were randomised (blinded prior to the trial start) to intervention or control (both n = 50). Outcomes included recruitment, attrition, adherence, and acceptability. Data were collected at baseline, two and four weeks. FINDINGS: Recruitment met a priori criteria (≥80%). There was no loss to follow-up, and no non-use, meeting adherence criteria (both ≤10%). Further, 48.0% (95% CI 33.7−62.6; n = 24) of households appropriately used and 56.0% (41.3−70.0; n = 28) cleaned the HPS over four weeks, partly meeting adherence criteria (≥50%). For acceptability, 41.0% (31.3−51.3; n = 41) of infants were in the HPS during random visits, failing criteria (≥50%). Further, the proportion of HPS use decreased during some activities, failing criteria (no decrease in use). A modified Barrier Analysis described good acceptability and multiple secondary benefits, including on women’s time burden and infant injury prevention. INTERPRETATION: Despite failing some a priori criteria, the trial demonstrated mixed adherence and good acceptability among intervention households. A definitive trial to determine efficacy is warranted if recommended adjustments are made. FUNDING: People In Need; Czech Development Agency. TRIAL REGISTRATION: RIDIE-ID-5de0b6938afb8.
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spelling pubmed-83129482021-07-31 A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study Budge, Sophie Hutchings, Paul Parker, Alison Tyrrel, Sean Norton, Sam Garbutt, Camila Woldemedhin, Fitsume Jemal, Mohammed Yasin Moges, Mathewos Hussen, Siraj Beyene, Hunachew PLoS Negl Trop Dis Research Article BACKGROUND: Water, sanitation and hygiene (WASH) interventions should support infant growth but trial results are inconsistent. Frequently, interventions do not consider behaviours or transmission pathways specific to age. A household playspace (HPS) is one intervention component which may block faecal-oral transmission. This study was a two-armed, parallel-group, randomised, controlled feasibility trial of a HPS in rural Ethiopia. It aimed to recommend proceeding to a definitive trial. Secondary outcomes included effects on infant health, injury prevention and women’s time. METHODS: November 2019−January 2020 106 households were identified and assessed for eligibility. Recruited households (N = 100) were randomised (blinded prior to the trial start) to intervention or control (both n = 50). Outcomes included recruitment, attrition, adherence, and acceptability. Data were collected at baseline, two and four weeks. FINDINGS: Recruitment met a priori criteria (≥80%). There was no loss to follow-up, and no non-use, meeting adherence criteria (both ≤10%). Further, 48.0% (95% CI 33.7−62.6; n = 24) of households appropriately used and 56.0% (41.3−70.0; n = 28) cleaned the HPS over four weeks, partly meeting adherence criteria (≥50%). For acceptability, 41.0% (31.3−51.3; n = 41) of infants were in the HPS during random visits, failing criteria (≥50%). Further, the proportion of HPS use decreased during some activities, failing criteria (no decrease in use). A modified Barrier Analysis described good acceptability and multiple secondary benefits, including on women’s time burden and infant injury prevention. INTERPRETATION: Despite failing some a priori criteria, the trial demonstrated mixed adherence and good acceptability among intervention households. A definitive trial to determine efficacy is warranted if recommended adjustments are made. FUNDING: People In Need; Czech Development Agency. TRIAL REGISTRATION: RIDIE-ID-5de0b6938afb8. Public Library of Science 2021-07-14 /pmc/articles/PMC8312948/ /pubmed/34260591 http://dx.doi.org/10.1371/journal.pntd.0009514 Text en © 2021 Budge et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Budge, Sophie
Hutchings, Paul
Parker, Alison
Tyrrel, Sean
Norton, Sam
Garbutt, Camila
Woldemedhin, Fitsume
Jemal, Mohammed Yasin
Moges, Mathewos
Hussen, Siraj
Beyene, Hunachew
A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study
title A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study
title_full A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study
title_fullStr A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study
title_full_unstemmed A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study
title_short A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study
title_sort randomised controlled feasibility trial of a babywash household playspace: the campi study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312948/
https://www.ncbi.nlm.nih.gov/pubmed/34260591
http://dx.doi.org/10.1371/journal.pntd.0009514
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