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Myositis in a patient with coronavirus disease 2019: A rare presentation

The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of sub...

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Detalles Bibliográficos
Autores principales: Gupta, Salil, Dixit, Prashant Kumar, Prasad, Ajay Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313044/
https://www.ncbi.nlm.nih.gov/pubmed/34334917
http://dx.doi.org/10.1016/j.mjafi.2020.10.015
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author Gupta, Salil
Dixit, Prashant Kumar
Prasad, Ajay Shankar
author_facet Gupta, Salil
Dixit, Prashant Kumar
Prasad, Ajay Shankar
author_sort Gupta, Salil
collection PubMed
description The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of subacute onset and progressive symmetrical proximal muscle weakness of both upper limbs and lower limbs with no sensory, cranial nerve deficit. She had elevated creatine phosphokinase levels of 906 U/L, an aspartate aminotransferase level of 126 IU/L, a lactate dehydrogenase level of 354 U/L, and an erythrocyte sedimentation rate of 68 mm/1 hr, and magnetic resonance imaging of the pelvis and thigh revealed muscle edema suggestive of myositis. Her reverse transcriptase-polymerase chain reaction result for SARS-CoV-2 was positive. Her evaluation for other causes of myositis was negative. She was managed with intravenous immunoglobulins and supportive care. She showed rapid improvement in symptoms and motor weakness. To our knowledge, this is the first reported case of COVID-19 related disabling myositis in India.
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spelling pubmed-83130442021-07-26 Myositis in a patient with coronavirus disease 2019: A rare presentation Gupta, Salil Dixit, Prashant Kumar Prasad, Ajay Shankar Med J Armed Forces India Case Report The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of subacute onset and progressive symmetrical proximal muscle weakness of both upper limbs and lower limbs with no sensory, cranial nerve deficit. She had elevated creatine phosphokinase levels of 906 U/L, an aspartate aminotransferase level of 126 IU/L, a lactate dehydrogenase level of 354 U/L, and an erythrocyte sedimentation rate of 68 mm/1 hr, and magnetic resonance imaging of the pelvis and thigh revealed muscle edema suggestive of myositis. Her reverse transcriptase-polymerase chain reaction result for SARS-CoV-2 was positive. Her evaluation for other causes of myositis was negative. She was managed with intravenous immunoglobulins and supportive care. She showed rapid improvement in symptoms and motor weakness. To our knowledge, this is the first reported case of COVID-19 related disabling myositis in India. Elsevier 2021-07 2021-07-26 /pmc/articles/PMC8313044/ /pubmed/34334917 http://dx.doi.org/10.1016/j.mjafi.2020.10.015 Text en © 2021 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.
spellingShingle Case Report
Gupta, Salil
Dixit, Prashant Kumar
Prasad, Ajay Shankar
Myositis in a patient with coronavirus disease 2019: A rare presentation
title Myositis in a patient with coronavirus disease 2019: A rare presentation
title_full Myositis in a patient with coronavirus disease 2019: A rare presentation
title_fullStr Myositis in a patient with coronavirus disease 2019: A rare presentation
title_full_unstemmed Myositis in a patient with coronavirus disease 2019: A rare presentation
title_short Myositis in a patient with coronavirus disease 2019: A rare presentation
title_sort myositis in a patient with coronavirus disease 2019: a rare presentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313044/
https://www.ncbi.nlm.nih.gov/pubmed/34334917
http://dx.doi.org/10.1016/j.mjafi.2020.10.015
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