Cargando…
Myositis in a patient with coronavirus disease 2019: A rare presentation
The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of sub...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313044/ https://www.ncbi.nlm.nih.gov/pubmed/34334917 http://dx.doi.org/10.1016/j.mjafi.2020.10.015 |
_version_ | 1783729250389458944 |
---|---|
author | Gupta, Salil Dixit, Prashant Kumar Prasad, Ajay Shankar |
author_facet | Gupta, Salil Dixit, Prashant Kumar Prasad, Ajay Shankar |
author_sort | Gupta, Salil |
collection | PubMed |
description | The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of subacute onset and progressive symmetrical proximal muscle weakness of both upper limbs and lower limbs with no sensory, cranial nerve deficit. She had elevated creatine phosphokinase levels of 906 U/L, an aspartate aminotransferase level of 126 IU/L, a lactate dehydrogenase level of 354 U/L, and an erythrocyte sedimentation rate of 68 mm/1 hr, and magnetic resonance imaging of the pelvis and thigh revealed muscle edema suggestive of myositis. Her reverse transcriptase-polymerase chain reaction result for SARS-CoV-2 was positive. Her evaluation for other causes of myositis was negative. She was managed with intravenous immunoglobulins and supportive care. She showed rapid improvement in symptoms and motor weakness. To our knowledge, this is the first reported case of COVID-19 related disabling myositis in India. |
format | Online Article Text |
id | pubmed-8313044 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-83130442021-07-26 Myositis in a patient with coronavirus disease 2019: A rare presentation Gupta, Salil Dixit, Prashant Kumar Prasad, Ajay Shankar Med J Armed Forces India Case Report The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of subacute onset and progressive symmetrical proximal muscle weakness of both upper limbs and lower limbs with no sensory, cranial nerve deficit. She had elevated creatine phosphokinase levels of 906 U/L, an aspartate aminotransferase level of 126 IU/L, a lactate dehydrogenase level of 354 U/L, and an erythrocyte sedimentation rate of 68 mm/1 hr, and magnetic resonance imaging of the pelvis and thigh revealed muscle edema suggestive of myositis. Her reverse transcriptase-polymerase chain reaction result for SARS-CoV-2 was positive. Her evaluation for other causes of myositis was negative. She was managed with intravenous immunoglobulins and supportive care. She showed rapid improvement in symptoms and motor weakness. To our knowledge, this is the first reported case of COVID-19 related disabling myositis in India. Elsevier 2021-07 2021-07-26 /pmc/articles/PMC8313044/ /pubmed/34334917 http://dx.doi.org/10.1016/j.mjafi.2020.10.015 Text en © 2021 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd. |
spellingShingle | Case Report Gupta, Salil Dixit, Prashant Kumar Prasad, Ajay Shankar Myositis in a patient with coronavirus disease 2019: A rare presentation |
title | Myositis in a patient with coronavirus disease 2019: A rare presentation |
title_full | Myositis in a patient with coronavirus disease 2019: A rare presentation |
title_fullStr | Myositis in a patient with coronavirus disease 2019: A rare presentation |
title_full_unstemmed | Myositis in a patient with coronavirus disease 2019: A rare presentation |
title_short | Myositis in a patient with coronavirus disease 2019: A rare presentation |
title_sort | myositis in a patient with coronavirus disease 2019: a rare presentation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313044/ https://www.ncbi.nlm.nih.gov/pubmed/34334917 http://dx.doi.org/10.1016/j.mjafi.2020.10.015 |
work_keys_str_mv | AT guptasalil myositisinapatientwithcoronavirusdisease2019ararepresentation AT dixitprashantkumar myositisinapatientwithcoronavirusdisease2019ararepresentation AT prasadajayshankar myositisinapatientwithcoronavirusdisease2019ararepresentation |