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Investigating the physiological relevance of ex vivo disc organ culture nutrient microenvironments using in silico modeling and experimental validation

BACKGROUND: Ex vivo disc organ culture systems have become a valuable tool for the development and pre‐clinical testing of potential intervertebral disc (IVD) regeneration strategies. Bovine caudal discs have been widely selected due to their large availability and comparability to human IVDs in ter...

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Detalles Bibliográficos
Autores principales: McDonnell, Emily E., Buckley, Conor T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313156/
https://www.ncbi.nlm.nih.gov/pubmed/34337330
http://dx.doi.org/10.1002/jsp2.1141