Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection

PURPOSE: To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. METHODS: Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision l...

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Autores principales: Gonzalez, Monica P., Rios, Radames, Pappaterra, Mariella, Hernandez, Miguel, Toledo, Allison, Santos, Carmen, Emanuelli, Andres, Kurup, Shree K., Oliver, Armando L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313348/
https://www.ncbi.nlm.nih.gov/pubmed/34336325
http://dx.doi.org/10.1155/2021/7336488
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author Gonzalez, Monica P.
Rios, Radames
Pappaterra, Mariella
Hernandez, Miguel
Toledo, Allison
Santos, Carmen
Emanuelli, Andres
Kurup, Shree K.
Oliver, Armando L.
author_facet Gonzalez, Monica P.
Rios, Radames
Pappaterra, Mariella
Hernandez, Miguel
Toledo, Allison
Santos, Carmen
Emanuelli, Andres
Kurup, Shree K.
Oliver, Armando L.
author_sort Gonzalez, Monica P.
collection PubMed
description PURPOSE: To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. METHODS: Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA. CONCLUSIONS: Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis.
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spelling pubmed-83133482021-07-31 Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection Gonzalez, Monica P. Rios, Radames Pappaterra, Mariella Hernandez, Miguel Toledo, Allison Santos, Carmen Emanuelli, Andres Kurup, Shree K. Oliver, Armando L. Case Rep Ophthalmol Med Case Report PURPOSE: To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. METHODS: Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA. CONCLUSIONS: Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis. Hindawi 2021-07-16 /pmc/articles/PMC8313348/ /pubmed/34336325 http://dx.doi.org/10.1155/2021/7336488 Text en Copyright © 2021 Monica P. Gonzalez et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gonzalez, Monica P.
Rios, Radames
Pappaterra, Mariella
Hernandez, Miguel
Toledo, Allison
Santos, Carmen
Emanuelli, Andres
Kurup, Shree K.
Oliver, Armando L.
Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_full Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_fullStr Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_full_unstemmed Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_short Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
title_sort reactivation of acute retinal necrosis following sars-cov-2 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313348/
https://www.ncbi.nlm.nih.gov/pubmed/34336325
http://dx.doi.org/10.1155/2021/7336488
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