The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis

PURPOSE: The NLRP3 inflammasome is a substantial component of the inflammation process. The complex pathogenesis of and the implication of a vast number of components in the inflammasome-activation pathway prompted us to search for compounds that have a wide therapeutic index and act at the level of...

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Detalles Bibliográficos
Autores principales: Saber, Sameh, Yahya, Galal, Gobba, Naglaa A, Sharaf, Hossam, Alshaman, Reem, Alattar, Abdullah, Amin, Noha A, El-Shedody, Ruwyda, Aboutouk, Farah H, Abd El-Galeel, Yumna, El-Hefnawy, Amr, Shabaka, Dina, Khalifa, Arwa, Saleh, Renad, Osama, Donya, El-Zoghby, Ghada, Youssef, Mahmoud E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313402/
https://www.ncbi.nlm.nih.gov/pubmed/34321905
http://dx.doi.org/10.2147/JIR.S315938

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