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Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study
PURPOSE: To integrate dose-averaged linear energy transfer (LET(d)) into spot-scanning proton arc therapy (SPArc) optimization and to explore its feasibility and potential clinical benefits. METHODS: An open-source proton planning platform (OpenREGGUI) has been modified to incorporate LET(d) into op...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313436/ https://www.ncbi.nlm.nih.gov/pubmed/34327139 http://dx.doi.org/10.3389/fonc.2021.698537 |