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Sildenafil ameliorates leptin resistance and normalizes lipid handling in the hypothalamic and adipose tissues of testosterone-exposed pregnant rats

Leptin and hypothalamic-adipose lipid handling are relevant in determining the shift of metabolic activities. There are scanty findings connecting glucose dysregulation as a result of hyperandrogenism during gestation to hypothalamic-adipose axis and leptin resistance. Sildenafil has recently gained...

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Detalles Bibliográficos
Autores principales: Areola, Emmanuel Damilare, Sabinari, Isaiah Woru, Usman, Taofeek Olumayowa, Abayomi, Faith Ifeoluwa, Onyezia, Onyeka, Onaolapo, Bisola, Adetokunbo, Phebe Oluwaseun, Adebanjo, Olympus Oyewole, Oladipupo, Funmilayo Rebecca, Olatunji, Lawrence Aderemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313495/
https://www.ncbi.nlm.nih.gov/pubmed/34337184
http://dx.doi.org/10.1016/j.heliyon.2021.e07574

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