Cargando…
Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors
Anopheles coluzzii females, important malaria vectors in Africa, mate only once in their lifetime. Mating occurs in aerial swarms with a high male-to-female ratio, where traits underlying male mating success are largely unknown. Here, we investigated whether cuticular hydrocarbons (CHCs) influence m...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313523/ https://www.ncbi.nlm.nih.gov/pubmed/34312484 http://dx.doi.org/10.1038/s42003-021-02434-1 |
_version_ | 1783729366822289408 |
---|---|
author | Adams, Kelsey L. Sawadogo, Simon P. Nignan, Charles Niang, Abdoulaye Paton, Douglas G. Robert Shaw, W. South, Adam Wang, Jennifer Itoe, Maurice A. Werling, Kristine Dabiré, Roch K. Diabaté, Abdoulaye Catteruccia, Flaminia |
author_facet | Adams, Kelsey L. Sawadogo, Simon P. Nignan, Charles Niang, Abdoulaye Paton, Douglas G. Robert Shaw, W. South, Adam Wang, Jennifer Itoe, Maurice A. Werling, Kristine Dabiré, Roch K. Diabaté, Abdoulaye Catteruccia, Flaminia |
author_sort | Adams, Kelsey L. |
collection | PubMed |
description | Anopheles coluzzii females, important malaria vectors in Africa, mate only once in their lifetime. Mating occurs in aerial swarms with a high male-to-female ratio, where traits underlying male mating success are largely unknown. Here, we investigated whether cuticular hydrocarbons (CHCs) influence mating success in natural mating swarms in Burkina Faso. As insecticides are widely used in this area for malaria control, we also determined whether CHCs affect insecticide resistance levels. We find that mated males have higher CHC abundance than unmated controls, suggesting CHCs could be determinants of mating success. Additionally, mated males have higher insecticide resistance under pyrethroid challenge, and we show a link between resistance intensity and CHC abundance. Taken together, our results suggest that CHC abundance may be subject to sexual selection in addition to selection by insecticide pressure. This has implications for insecticide resistance management, as these traits may be sustained in the population due to their benefits in mating even in the absence of insecticides. |
format | Online Article Text |
id | pubmed-8313523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-83135232021-08-03 Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors Adams, Kelsey L. Sawadogo, Simon P. Nignan, Charles Niang, Abdoulaye Paton, Douglas G. Robert Shaw, W. South, Adam Wang, Jennifer Itoe, Maurice A. Werling, Kristine Dabiré, Roch K. Diabaté, Abdoulaye Catteruccia, Flaminia Commun Biol Article Anopheles coluzzii females, important malaria vectors in Africa, mate only once in their lifetime. Mating occurs in aerial swarms with a high male-to-female ratio, where traits underlying male mating success are largely unknown. Here, we investigated whether cuticular hydrocarbons (CHCs) influence mating success in natural mating swarms in Burkina Faso. As insecticides are widely used in this area for malaria control, we also determined whether CHCs affect insecticide resistance levels. We find that mated males have higher CHC abundance than unmated controls, suggesting CHCs could be determinants of mating success. Additionally, mated males have higher insecticide resistance under pyrethroid challenge, and we show a link between resistance intensity and CHC abundance. Taken together, our results suggest that CHC abundance may be subject to sexual selection in addition to selection by insecticide pressure. This has implications for insecticide resistance management, as these traits may be sustained in the population due to their benefits in mating even in the absence of insecticides. Nature Publishing Group UK 2021-07-26 /pmc/articles/PMC8313523/ /pubmed/34312484 http://dx.doi.org/10.1038/s42003-021-02434-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Adams, Kelsey L. Sawadogo, Simon P. Nignan, Charles Niang, Abdoulaye Paton, Douglas G. Robert Shaw, W. South, Adam Wang, Jennifer Itoe, Maurice A. Werling, Kristine Dabiré, Roch K. Diabaté, Abdoulaye Catteruccia, Flaminia Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
title | Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
title_full | Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
title_fullStr | Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
title_full_unstemmed | Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
title_short | Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
title_sort | cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313523/ https://www.ncbi.nlm.nih.gov/pubmed/34312484 http://dx.doi.org/10.1038/s42003-021-02434-1 |
work_keys_str_mv | AT adamskelseyl cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT sawadogosimonp cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT nignancharles cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT niangabdoulaye cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT patondouglasg cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT robertshaww cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT southadam cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT wangjennifer cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT itoemauricea cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT werlingkristine cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT dabirerochk cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT diabateabdoulaye cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors AT catterucciaflaminia cuticularhydrocarbonsareassociatedwithmatingsuccessandinsecticideresistanceinmalariavectors |